| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 320 (222.162) | 05.2014 - | 200kW / 272HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 400 (222.165) | 2014-03 - 2017-05 | 245kW / 333HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 400 4-matic (222.067, 222.167) | 2014-11 - 2017-05 | 245kW / 333HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 450 (222.066, 222.166) | 2017-02 - | 270kW / 367HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 450 4-matic (222.064, 222.164, 222.964) | 2017-02 - | 270kW / 367HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 500 (222.082, 222.182) | 2013-05 - 2017-05 | 335kW / 455HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 500 4-matic (222.085, 222.185) | 2013-05 - 2017-05 | 335kW / 455HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 560 (222.083, 222.183) | 2017-07 - | 345kW / 469HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 560 4-matic (222.086, 222.186) | 2017-05 - | 345kW / 469HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 350 BlueTEC 4-matic (222.133) | 2014-02 - 2017-05 | 185kW / 252HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 350 BlueTEC / d (222.132, 222.032, 222.123) | 2013-05 - 2017-05 | 190kW / 258HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 350 BlueTEC / d 4-matic (222.033, 222.133) | 2014-02 - 2017-05 | 190kW / 258HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 350 d (222.020, 222.120) | 2017-07 - | 210kW / 286HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 350 d 4-matic (222.021, 222.121) | 2017-05 - | 210kW / 286HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 400 d (222.034, 222.134) | 2017-07 - | 250kW / 340HP |
| MERCEDES-BENZ S-CLASS (W222, V222, X222) S 400 d 4-matic (222.035, 222.135) | 2017-05 - | 250kW / 340HP |